A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate.

Abstract	A reaction of gold(I) thiomalates [Au(tm)], "Myocrisin" (an antiarthritic drug), with captopril (a high blood pressure drug) was carried out in aqueous solution at pH 7.20 using 13C NMR spectroscopy. Captopril, which exists in the cis (c) and trans (t) isomer forms, binds strongly with gold(I), ejecting thiomalate (Htm) as free ligand into solution.
Authors	A A Isab
Journal	Journal of inorganic biochemistry (J Inorg Biochem) Vol. 30 Issue 1 Pg. 69-75 (May 1987) ISSN: 0162-0134 [Print] United States
PMID	3108454 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Gold Sodium Thiomalate Captopril
Topics	Captopril Chemical Phenomena Chemistry Gold Sodium Thiomalate Hydrogen-Ion Concentration Isomerism Magnetic Resonance Spectroscopy

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