Midface Growth in Patients With Unilateral Cleft Lip and Palate Treated With a Nasoalveolar Molding Protocol.

Abstract

This retrospective cohort study aimed to determine the impact of a nasoalveolar molding (NAM) protocol on midface growth in school-aged children with non-syndromic unilateral cleft lip and palate (UCLP). Data from 56 consecutively treated, NAM-prepared, Caucasian patients with non-syndromic UCLP from a single US cleft palate center were compared to pooled center data based on 56 patients with non-syndromic UCLP treated at 2 Eurocleft centers that did not use presurgical infant orthopedics (non-PSIO). Lateral cephalograms were obtained and 28 landmarks were identified. Published cephalometric measurements from Eurocleft centers were used for comparison. Seven cephalometric measurements (SNA, SNB, ANB, A'N'B', G'-Sn'-Pg', Sn-CT-LS, ANS-Me/N-Me%), available or derivable for both centers, were analyzed. Means and standard deviations for the 7 measurements were calculated for the NAM center. Student's t-tests were used to compare group means for 6 of the measures and a test of proportion was used for ANS-Me/N-Me%. No significant differences were found between the NAM protocol-prepared group and the Eurocleft non-PSIO centers on any of the 7 analyzed cephalometric relationships after accounting for false discovery rate. The NAM treatment protocol does not appear to impact skeletal or soft tissue facial growth in school-aged children with non-syndromic UCLP.

• Authors: Marcie S Rubin, Sean A P Clouston, Elçin Esenlik, Pradip R Shetye, Roberto L Flores, Barry H Grayson
• Journal: The Journal of craniofacial surgery (J Craniofac Surg) Vol. 30 Issue 6 Pg. 1640-1643 (Sep 2019) ISSN: 1536-3732 [Electronic] United States
• PMID: 30950956 (Publication Type: Journal Article)

Topics

• Cephalometry (methods)
• Child
• Cleft Lip (surgery)
• Cleft Palate (surgery)
• Face (surgery)
• Female
• Humans
• Male
• Maxillofacial Development
• Orthopedic Procedures
• Retrospective Studies