[Radiotherapy in juvenile xanthogranuloma of the iris].

Abstract

Nevoxanthoendotheliomas (and juvenile xanthogranulomas) are very rare benign skin diseases which occur in infants. An ocular manifestation, mainly in the iris, has been found in approximately. 10% of the cases, The clinical picture is characterized by a recurrent unilateral hemorrhage of the anterior chamber, which is the reason for seeing an ophthalmologist. The clinical diagnosis of juvenile xanthogranuloma is based on the characteristic iris changes - heterochromia, circumscribed vascularized tumor, or diffuse thickening of the iris. Sometimes elevated intraocular pressure is also found. In combination with a mild local steroid, radiotherapy with 300 to 400 cGy should be started immediately in order to prevent a sometimes uncontrollable secondary glaucoma. The good results achieved in 5 of the authors' own cases underline the value of low-dose radiotherapy in this disease: the affected eye was healed in all 5 cases.

• Authors: R P Müller, H Busse
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 189 Issue 1 Pg. 15-8 (Jul 1986) ISSN: 0023-2165 [Print] Germany
• Vernacular Title: Strahlentherapie bei juvenilem Xanthogranulom der Iris.
• PMID: 3093751 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Child, Preschool
• Female
• Humans
• Infant
• Iris Diseases (diagnosis, radiotherapy)
• Male
• Radiotherapy Dosage
• Xanthogranuloma, Juvenile (diagnosis, radiotherapy)