Role of debridement and interferon in the treatment of dendritic keratitis.

Abstract

In a controlled clinical study, 42 patients with dendritic keratitis were treated either with thermocautery plus human leukocyte interferon (HLI) or with minimal wiping debridement plus HLI. The results show that the efficiency with which primary debridement was carried out, determined the success of further therapy using interferon. We conclude that interferon works basically as a prophylactic agent and needs the support of further antiviral measures to be effective against dendritic keratitis.

• Authors: R Sundmacher, K Cantell, P Haug, D Neumann-Haefelin
• Journal: Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology (Albrecht Von Graefes Arch Klin Exp Ophthalmol) Vol. 207 Issue 2 Pg. 77-82 (Jul 17 1978) ISSN: 0065-6100 [Print] Germany
• PMID: 308783 (Publication Type: Journal Article)

Chemical References

• Interferons

Topics

• Debridement
• Electrocoagulation
• Humans
• Interferons (therapeutic use)
• Keratitis, Dendritic (drug therapy, surgery, therapy)
• Leukocytes