[Cancer immune therapy for the treatment of haematological malignancies].

Abstract

Cancer immune therapy is now used routinely for the treatment of several solid malignancies, albeit just recently having entered the clinic for treatment of haematological malignancies. Several studies demonstrate that cancer immune therapy is a promising treatment modality for the latter. Especially treatment with chimeric antigen receptor T cells for acute lymphoblastic leukaemia and lymphoma is promising. Other promising treatment modalities are immune check point inhibitors for both lymphoid and myeloid malignancies, as well as therapeutic cancer vaccination targeting tumour antigens.

• Authors: Morten Orebo Holmström, Uffe Klausen, Nicolai Grønne Jørgensen, Staffan Holmberg, Jacob Grauslund, Özcan Met, Inde Marie Svane, Lars Møller Pedersen, Lene Meldgaard Knudsen, Hans Carl Hasselbalch, Mads Hald Andersen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 181 Issue 10 (Mar 04 2019) ISSN: 1603-6824 [Electronic] Denmark
• PMID: 30869069 (Publication Type: Journal Article)

Chemical References

• Antigens, Neoplasm

Topics

• Antigens, Neoplasm
• Hematologic Neoplasms (therapy)
• Humans
• Immunotherapy
• Myeloproliferative Disorders