Abstract |
The sickle cell diseases are a major health problem for Afro-Caribbean peoples. Neonatal detection and prophylactic management can reduce mortality and morbidity in childhood. A study was therefore conducted analysing the results of the first two years of cord blood screening in the Camberwell health area. Thirteen cases of sickle cell disease and two of haemoglobin (Hb)C disease were identified among 2202 non-white infants screened. The carrier state, sickle cell trait (HbAS), was present in 11.9% and HbC trait (HbAC) in 4.1% of Afro-Caribbean infants. The incidence of disease and of carrier states was much higher in West Africans than in Caribbeans. The wider implications of screening and the need for a comprehensive plan of care are emphasised.
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Authors | M E Horn, M C Dick, B Frost, L R Davis, A J Bellingham, C E Stroud, J W Studd |
Journal | British medical journal (Clinical research ed.)
(Br Med J (Clin Res Ed))
Vol. 292
Issue 6522
Pg. 737-40
(Mar 15 1986)
ISSN: 0267-0623 [Print] England |
PMID | 3082419
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Anemia, Sickle Cell
(epidemiology)
- Child, Preschool
- Costs and Cost Analysis
- Ethnicity
- Fetal Blood
(analysis)
- Hemoglobin SC Disease
(epidemiology)
- Humans
- Infant
- Infant, Newborn
- London
- Mass Screening
(economics)
- Pilot Projects
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