[Preoperative hemodilution for the prevention of postoperative deep venous thrombosis and early infectious complications in colorectal resections].

Abstract

The effectiveness of heparin DHE and preoperative haemodilution (M.N.H.) for prophylaxis against deep venous thrombosis (D.V.T.) and against early septic complications was investigated in a prospective controlled study on two comparable groups of patients who had undergone colorectal resections for malignant tumours. The results clearly suggested that there was no significant difference between heparin DHE and preoperative haemodilution for prophylactic effectiveness on D.V.T. yet, the percentage of postoperative septic early complications, that is insufficiency of anastomosis and abdominal wall infections, was much lower (p less than 0.001) in patients with moderate normovolaemic haemodilution (haematocrit = 30 per cent). While the number of cases reviewed was as low as 62, the point can be made that less postoperative septic complications occurred to patients with low haematocrit (30 per cent).

• Authors: R Vara-Thorbeck, J Rosell, M Salvi, C Vara-Thorbeck
• Journal: Zentralblatt fur Chirurgie (Zentralbl Chir) Vol. 113 Issue 18 Pg. 1204-9 ( 1988) ISSN: 0044-409X [Print] Germany
• Vernacular Title: Präoperative Hämodilution als Prophylaxe der postoperativen tiefen Venenthrombose und septischer Frühkomplikationen bei kolorektalen Resektionen.
• PMID: 3068936 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Heparin, Low-Molecular-Weight
• heparin-dihydergot
• Dihydroergotamine
• Heparin

Topics

• Clinical Trials as Topic
• Colonic Neoplasms (surgery)
• Dihydroergotamine (administration & dosage)
• Drug Combinations (administration & dosage)
• Hemodilution
• Heparin (administration & dosage)
• Heparin, Low-Molecular-Weight
• Humans
• Middle Aged
• Postoperative Complications (prevention & control)
• Premedication
• Prospective Studies
• Rectal Neoplasms (surgery)
• Surgical Wound Infection (prevention & control)
• Thrombophlebitis (prevention & control)