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Electron microscopy proves Jo-1 antigen to be predominantly cytoplasmic but also nuclear.

Abstract
The Jo-1 antigen is a specific marker for autoimmune myositis with an excellent correlation with associated interstitial lung disease. Using an electron microscopy immunogold technique, we were able to show that the antigen was predominantly cytoplasmic.
AuthorsM Thiry, R Humbel, M Dicato, G Goessens, R Meyers, F Ries
JournalBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (Biomed Pharmacother) Vol. 42 Issue 7 Pg. 469-71 ( 1988) ISSN: 0753-3322 [Print] France
PMID3066408 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Amino Acyl-tRNA Synthetases
  • Histidine-tRNA Ligase
Topics
  • Amino Acyl-tRNA Synthetases (analysis)
  • Cell Nucleus (immunology)
  • Cytoplasm (immunology, ultrastructure)
  • Female
  • Histidine-tRNA Ligase (analysis)
  • Humans
  • Immunologic Techniques
  • Microscopy, Electron
  • Middle Aged
  • Myositis (immunology)
  • Scleroderma, Systemic (immunology)

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