[A case of neonatal meningitis due to Flavobacterium meningosepticum successfully treated with cefmetazole and cefotaxime].

Abstract

A 3-day-old male infant, weighing 3,413 g and a gestational age of 38 weeks developed neonatal meningitis due to Flavobacterium meningosepticum. Treatment with cefmetazole and cefotaxime led him to a complete recovery without neurologic deficit. Of 82 previously published cases under 1 year old, 41 cases died and 16 of survivors developed hydrocephalus because the organism was resistant to many antibiotics. Therapy of meningitis due to the organism has not been standardized but the early laboratory identification and the choice of effective and safe antibiotics determined by antimicrobial sensitivity test improve the outcome.

• Authors: A Takeda, T Toyoura, K Kiyohara, M Shimohira, S Arai, C Fukuda
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 41 Issue 5 Pg. 557-62 (May 1988) ISSN: 0368-2781 [Print] Japan
• PMID: 3063849 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Cefmetazole
• Cefotaxime

Topics

• Cefmetazole (therapeutic use)
• Cefotaxime (therapeutic use)
• Flavobacterium (drug effects)
• Humans
• Infant, Newborn
• Male
• Meningitis (drug therapy, etiology)