[Immunoenzyme methods for determining thyroid hormones].

Abstract

The analytical reliability of the immunoenzyme methods for determination of the thyroid hormones thyroxin, triiodothyronine, thyroid-binding globulin, thyrotropic hormone and the thyroid-binding capacity was examined by the peroxidase activity of the marker enzyme of "Specol-11" 28 healthy controls, 28 patients with subcompensated insulin-dependent diabetes with mean duration of 8.4 years and 11 patients with hypogonadism were examined. In the diabetic patients were found changes in their thyroid state characteristic for hypothyroidism--increased thyroxin and a decrease of the thyroid-stimulating hormone with a lowered level of the binding proteins. The patients with hypogonadism showed changes mainly in the binding proteins level, a decrease of the thyroid-binding capacity with 70%. The results reveal interrelations between the thyroid gland hormonal state and other hormonal disorders.

• Authors: A Tsoncheva, D Dochev, A Tsanev, M Protich, I Daskalova
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 27 Issue 4 Pg. 73-7 ( 1988) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Imunoenzimni metodi za opredeliane na tireoidni khormoni.
• PMID: 3062896 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Thyroid Hormones
• Triiodothyronine
• Thyrotropin
• Thyroglobulin
• Thyroxine

Topics

• Adult
• Diabetes Mellitus, Type 1 (blood)
• Female
• Humans
• Immunoenzyme Techniques (instrumentation)
• Male
• Spectrophotometry (instrumentation)
• Thyroglobulin (blood)
• Thyroid Hormones (blood)
• Thyrotropin (blood)
• Thyroxine (blood)
• Triiodothyronine (blood)