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Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators.

Abstract
Activation of Toll-like receptors (TLRs) located on immune cells leads to induction of immune responses that can be useful in vaccines for infectious diseases, cancer immunotherapy, and autoimmune diseases. Novel TLR signaling pathway modulators can further enhance the efficacy of TLR ligands.
AuthorsNikunj M Shukla, Michael Chan, Tomoko Hayashi, Dennis A Carson, Howard B Cottam
JournalACS medicinal chemistry letters (ACS Med Chem Lett) Vol. 9 Issue 12 Pg. 1156-1159 (Dec 13 2018) ISSN: 1948-5875 [Print] United States
PMID30613317 (Publication Type: Editorial)

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