Abstract |
In a randomized, single-blind trial, 78 women having vaginal termination of pregnancy were treated with either a 1-mg gemeprost (Cervagem) pessary or a Lamicel tent inserted 3-4 h before operation. Both agents produced satisfactory cervical softening but dilatation was significantly easier after gemeprost. Pre-operative side-effects were more frequent after gemeprost but did not increase the need for analgesia. There were no differences between the two groups with regard to either postoperative symptoms and analgesic requirements or pre-operative and postoperative temperature, pulse rate and blood pressure. Gemeprost pessaries are easier, faster and less uncomfortable to administer.
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Authors | C W Helm, N Davies, R J Beard |
Journal | British journal of obstetrics and gynaecology
(Br J Obstet Gynaecol)
Vol. 95
Issue 9
Pg. 911-5
(Sep 1988)
ISSN: 0306-5456 [Print] England |
PMID | 3056505
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Abortifacient Agents
- Abortifacient Agents, Nonsteroidal
- Lamicel
- gemeprost
- Magnesium Sulfate
- Polyvinyl Alcohol
- Alprostadil
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Topics |
- Abortifacient Agents
- Abortifacient Agents, Nonsteroidal
- Abortion, Therapeutic
- Adult
- Alprostadil
(administration & dosage, analogs & derivatives)
- Cervix Uteri
(drug effects)
- Clinical Trials as Topic
- Dilatation and Curettage
- Female
- Humans
- Magnesium Sulfate
(administration & dosage)
- Pessaries
- Polyvinyl Alcohol
(administration & dosage)
- Pregnancy
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