[Neurologic manifestations of arterial hypertension in children].
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| Abstract |
Neurological complications of arterial hypertension are analyzed in 31 children (mean age = 9 years). All patients presented a renal or renovascular disease (acute nephritis + hypoplastic dysplasia , transplantation = 58%) for which malignant hypertension was the first symptom in 16%. The mean +/- SD initial blood pressure was 189 +/- 33/113 +/- 25 mm Hg and was preceded by previous symptoms in 1 patient out of 6. Neurological abnormalities consisted in seizures (48%), acute intracranial hypertension (39%), cranial palsy (23%), coma (19%), hemiplegia/paresia (16%), retinal changes (6%) or aphasia (6%). The EEG was abnormal in 50% of the patients, sometimes showing permanent paroxysmal activity. Neuroradiologic investigations revealed hemorrhagic and/or ischemic lesions in 1/5 patients. On follow-up, hypertension disappeared in 41% of the children; a decrease in renal function was noted in 56% of the patients at the last examination; neurological sequellae were present in 40% (EEG anomalies +/- epilepsy, motor deficit, retinal changes, psychomotor delay, cranial palsy) and 1 patient died. The morbidity of malignant hypertension stresses the importance of early diagnosis and treatment (calcium channel blockers) when its prevention is not possible.
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| Authors | P Cochat, M C Delmas, L de Parscau, D Floret, B Parchoux, P Guibaud, L David, F Larbre |
| Journal | Pediatrie (Pediatrie) Vol. 43 Issue 6 Pg. 551-6 ( 1988) ISSN: 0031-4021 [Print] France |
| Vernacular Title | Manifestations neurologiques de l'hypertension artérielle chez l'enfant. |
| PMID | 3054803 (Publication Type: Journal Article) |
| Chemical References |
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