[Familial deficiency of complement factor 7: association with bacterial meningitis. Apropos of 3 recent cases].

Abstract

Three recent cases of inherited deficiency of the seventh component of complement (C7) associated with recurrent infectious meningitis are described. Two cases were associated with meningococcal meningitis, the third is the first case report of C7 inherited deficiency associated with Haemophilus parainfluenzae meningitis. Family studies are consistent with inheritance and non-HLA-linked, autosomal codominant trait of the C7 deficiency. The three patients have remained well, following antibiotic treatment.

• Authors: M Drancourt, D Raoult, P Lesavre, H Gallais, P Casanova
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 36 Issue 6 Pg. 825-8 (Jun 1988) ISSN: 0369-8114 [Print] France
• Vernacular Title: Déficit familial en facteur sept du complément: association avec les méningites bactériennes. A propos de trois cas récents.
• PMID: 3047643 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Complement C7

Topics

• Adolescent
• Adult
• Complement C7 (deficiency)
• Female
• Humans
• Male
• Meningitis, Haemophilus (etiology, genetics)
• Meningitis, Meningococcal (etiology, genetics)
• Pedigree
• Recurrence