[Rickettsiaceae infections and fluoroquinolones].

Abstract

Twenty nine patients with Rickettsiosis (Tick born fever, n: 22, Q fever, n: 7) has been treated with fluoroquinolones. These compounds was used alone n: 25 (Pefloxacin, n: 15; Ofloxacin, n: 10) or associated n: 4 (Pefloxacin + Rifampin). The general efficacy was excellent. Common Tick born fever and pulmonary forms of Q fever was fast cured. Severe Tick born fever (neurologic or polyvisceral forms, n: 5) and Q fever with long term hyperthermia, n: 4 cas always cured without complications but the time necessary to obtain apyrexia was often longer (6 cases).

• Authors: A Bertrand, F Janbon, O Jonquet, J Reynes
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 36 Issue 5 Pg. 493-5 (May 1988) ISSN: 0369-8114 [Print] France
• Vernacular Title: Infections par les rickettsiales et fluoroquinolones.
• PMID: 3043346 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents
• Oxazines
• Pefloxacin
• Ofloxacin
• Norfloxacin
• Rifampin

Topics

• Administration, Oral
• Adult
• Aged
• Anti-Infective Agents (therapeutic use)
• Boutonneuse Fever (drug therapy)
• Drug Evaluation
• Drug Therapy, Combination
• Female
• Humans
• Injections, Intravenous
• Male
• Middle Aged
• Norfloxacin (administration & dosage, analogs & derivatives, therapeutic use)
• Ofloxacin
• Oxazines (administration & dosage, therapeutic use)
• Pefloxacin
• Pregnancy
• Q Fever (drug therapy)
• Rifampin (administration & dosage, therapeutic use)