Abstract | OBJECTIVES: METHODS: We performed a literature search for identifying eligible articles from PubMed database using the search terms " cervical cancer", "sentinel lymph node", " indocyanine green", "blue dyes", " human serum albumin", and " technetium-99 radiocolloid". We performed a meta-analysis. Comparison of the overall, bilateral, and unilateral detection rates of the different tracers was the primary goal. Comparison of the false-negative rate among the tracers was the secondary goal. RESULTS: Only eight retrospective studies including 661 patients were included. ICG versus combinations of three other tracers showed significantly higher bilateral and unilateral detection rates, but no difference in the overall rate of detecting SLNs. ICG had a higher bilateral detection rate than blue dye and technetium-99. Absorbing human serum albumin into ICG as a lymphatic tracer did not show a difference in detection rate compared with ICG alone. CONCLUSIONS:
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Authors | Qurat Ulain, Lu Han, Qian Wu, Lanbo Zhao, Qi Wang, Xiaoqian Tuo, Yiran Wang, Qing Wang, Sijia Ma, Chao Sun, Qing Song, Qiling Li |
Journal | The Journal of international medical research
(J Int Med Res)
Vol. 46
Issue 12
Pg. 4885-4897
(Dec 2018)
ISSN: 1473-2300 [Electronic] England |
PMID | 30360672
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
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Topics |
- Female
- Humans
- Image-Guided Biopsy
(methods)
- Indocyanine Green
- Sentinel Lymph Node
(diagnostic imaging, pathology, surgery)
- Sentinel Lymph Node Biopsy
(methods)
- Uterine Cervical Neoplasms
(diagnostic imaging, pathology, surgery)
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