Abstract | AIM: MATERIALS & METHODS: RESULTS: The tunable laser pulse-interaction time and repetition rate aided in generating programmable NiO nanomatrix chemistry. The nanomatrix mimicked extracellular matrix in physical configuration and properties presenting favorable cues to cancerous HeLa cell and fibroblast cell adhesion and proliferation without cytotoxicity. The 3D nanomatrix structure altered HeLa cell behavior and induced apoptosis cancer apoptosis with an evidence of increased endocytosis when compared with fibroblast cells. CONCLUSION:
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Authors | Sivaprasad C Vijayakumar, Krishnan Venkatakrishnan, Bo Tan |
Journal | Nanomedicine (London, England)
(Nanomedicine (Lond))
Vol. 13
Issue 19
Pg. 2469-2490
(10 2018)
ISSN: 1748-6963 [Electronic] England |
PMID | 30328379
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Apoptosis
(drug effects)
- Cell Adhesion
(drug effects)
- Cell Proliferation
(drug effects)
- Cell Survival
(drug effects)
- Extracellular Matrix
(chemistry, drug effects)
- Fibroblasts
(drug effects)
- HeLa Cells
- Humans
- Nanostructures
(chemistry, therapeutic use)
- Neoplasms
(pathology, therapy)
- Nickel
(chemistry)
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