Abstract |
Studies were performed to compare the therapeutic effectiveness of three antiviral drugs ( ARA-A, ARA-C and IDU) on the course of fatal disseminated vaccinia virus infection in immunosuppressed mice. Treatment with ARA-A begun as late as 7 days after virus infection was significantly effective in preventing death; no antiviral effect of the other two drugs was demonstrated.
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Authors | M Worthington, M Conliffe |
Journal | The Journal of general virology
(J Gen Virol)
Vol. 36
Issue 2
Pg. 329-333
(Aug 1977)
ISSN: 0022-1317 [Print] England |
PMID | 302323
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Antilymphocyte Serum
- Cytarabine
- Vidarabine
- Idoxuridine
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Topics |
- Animals
- Antilymphocyte Serum
(therapeutic use)
- Cytarabine
(administration & dosage, therapeutic use)
- Disease Models, Animal
- Drug Evaluation, Preclinical
- Idoxuridine
(administration & dosage, therapeutic use)
- Immunosuppression Therapy
- Injections, Intraperitoneal
- Mice
- T-Lymphocytes
(immunology)
- Vaccinia
(drug therapy, mortality)
- Vidarabine
(administration & dosage, therapeutic use)
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