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Fatal metastatic cystosarcoma phyllodes in an adolescent female: case report and review of treatment approaches.

AbstractThe third reported case of fatal malignant cystosarcoma phyllodes in an adolescent female is described. The patterns of local recurrence and distant spread in this case, including the response to treatment, were similar to those reported in the first reported case in this age group. A review of the treatment recommendations for cystosarcoma phyllodes revealed that the surgical procedure of choice for the malignant variant has remained controversial, and the conclusions regarding the ineffectiveness of radiation and chemotherapy have been based on insufficient data handed down through the years. Our observations in this case and the information we have obtained from the literature have prompted us to recommend a multidisciplinary approach for malignant cystosarcoma phyllodes, particularly in young women, and we are calling for a multi-institutional study group to further investigate this disease.
AuthorsC I Turalba, A M el-Mahdi, L Ladaga
JournalJournal of surgical oncology (J Surg Oncol) Vol. 33 Issue 3 Pg. 176-81 (Nov 1986) ISSN: 0022-4790 UNITED STATES
PMID3022078 (Publication Type: Case Reports, Journal Article)
Topics
  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Breast Neoplasms (pathology, therapy)
  • Combined Modality Therapy
  • Female
  • Humans
  • Lung Neoplasms (drug therapy, radiotherapy, secondary)
  • Phyllodes Tumor (pathology, therapy)