[Changes in the concentration of catecholamines in the organs of animals with experimental myocardial infarcts under the influence of malaben].

Abstract

The content of adrenaline and noradrenaline in the tissues of the heart, adrenal glands, spleen and brain of rats was studied in experimental myocardial infarction. A significant decrease in the catecholamine levels was revealed in the tissues. Malaben promoted normalization of the catecholamine tissue content in myocardial infarction. It is suggested that the said effect of malaben is due to its antihistaminic properties.

• Authors: E G Gromova
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 84 Issue 7 Pg. 49-51 (Jul 1977) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Izmenenie soderzhaniia katekholaminov v organakh zhivotnykh s éksperimental'nym infarktom miokarda pod vliianiem malabena.
• PMID: 302130 (Publication Type: Journal Article)

Chemical References

• Aminobenzoates
• Malonates
• para-Aminobenzoates
• disodium 4,4'-9((1,3-dioxo-1,3-propanediyl)diimino)dibenzoate
• 4-Aminobenzoic Acid
• Norepinephrine
• Epinephrine

Topics

• 4-Aminobenzoic Acid (therapeutic use)
• Adrenal Glands (metabolism)
• Aminobenzoates (therapeutic use)
• Animals
• Brain (metabolism)
• Epinephrine (metabolism)
• Malonates (therapeutic use)
• Myocardial Infarction (drug therapy, metabolism)
• Myocardium (metabolism)
• Norepinephrine (metabolism)
• Rats
• Spleen (metabolism)
• para-Aminobenzoates