Appropriateness of Beta-Lactam Allergy Record Updates After an Allergy Service Consult.

Abstract

BACKGROUND:

Many patients with a self-reported penicillin allergy go on to tolerate beta-lactam antibiotics. Allergy specialists may be consulted to determine the nature and extent of the allergy. However, electronic allergy records must be appropriately updated such that recommendations are carried forward.

OBJECTIVE:

To determine the percentage of patients who have their electronic allergy record updated after an allergy service consult (ASC).

METHODS:

This was a retrospective study of patients with at least 1 documented beta-lactam allergy and had an ASC during (inpatient) or prior to (outpatient) hospital admission at Northwestern Memorial Hospital and Prentice Women's Hospital in Chicago, Illinois.

RESULTS:

Within the study period, a total of 26 526 patients were identified as having a documented antibiotic allergy, with 21 657 patients (81.6% of patients with allergies) having a listed beta-lactam allergy. Of these patients, 1689 (7.8%) patients were identified as having an ASC during or prior to admission, with 598 patients meeting inclusion criteria. Changes in the allergy record were recommended by the ASC for 62% (n = 371) of patients; however, the allergy record was updated after the ASC in 74.9% (n = 278) of patients.

CONCLUSION:

ASC recommendations to delabel a patient as beta-lactam allergic must result in updating the allergy record in order to optimize future treatment. Given the low proportion of allergy-labeled patients tested, programs outside formal ASCs should be considered.

• Authors: Bryan G Shaw, Inela Masic, Nancy Gorgi, Niree Kalfayan, Elise M Gilbert, Viktorija O Barr, Michael G Ison, Milena M McLaughlin
• Journal: Journal of pharmacy practice (J Pharm Pract) Vol. 33 Issue 3 Pg. 243-246 (Jun 2020) ISSN: 1531-1937 [Electronic] United States
• PMID: 30180773 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Penicillins
• beta-Lactams

Topics

• Anti-Bacterial Agents (adverse effects)
• Drug Hypersensitivity (diagnosis, epidemiology)
• Female
• Humans
• Illinois
• Penicillins (adverse effects)
• Retrospective Studies
• beta-Lactams (adverse effects)