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The treatment of advanced histiocytosis-X with sequential hemibody irradiation.

Abstract
A patient with systemic histiocytosis was treated with hemibody irradiation, vincristine, and prednisone. The patient died of an extensive peripheral neuropathy. An autopsy revealed gross histiocytosis-X involvement of the unirradiated tissues, and no evidence of disease within the field of irradiation. A treatment protocol employing sequential hemibody irradiation is discussed.
AuthorsT W Griffin
JournalCancer (Cancer) Vol. 39 Issue 6 Pg. 2435-6 (Jun 1977) ISSN: 0008-543X [Print] United States
PMID301431 (Publication Type: Journal Article)
Chemical References
  • Vincristine
  • Prednisone
Topics
  • Histiocytosis, Langerhans-Cell (drug therapy, radiotherapy)
  • Humans
  • Infant
  • Male
  • Prednisone (therapeutic use)
  • Vincristine (adverse effects, therapeutic use)

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