Abstract |
The ability of conventional virus receptors to mediate infection and transformation of immature B cells by the avian leukosis virus (ALV) was analyzed in chimeric chickens whose bursa of Fabricius contained a mixture of B cells from subgroup A virus receptor-positive and -negative chickens. The data indicate that factors that determine resistance of fibroblasts to ALV infection also apply to bursal cells and that other receptors expressed by B cells, i.e., antigen or mitogen receptors, do not initiate infection or transformation, at least not independent of conventional virus receptors.
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Authors | D L Ewert, C Goldstein |
Journal | Virology
(Virology)
Vol. 152
Issue 1
Pg. 262-7
(Jul 15 1986)
ISSN: 0042-6822 [Print] United States |
PMID | 3012871
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Animals
- Avian Leukosis
(microbiology)
- Avian Sarcoma Viruses
(growth & development)
- B-Lymphocytes
(microbiology)
- Bursa of Fabricius
(microbiology)
- Chickens
(microbiology)
- Chimera
- Fibroblasts
(microbiology)
- Liver Neoplasms
(secondary)
- Receptors, Virus
(physiology)
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