Abstract | INTRODUCTION:
Hepatitis B is a serious public health problem across sub-Saharan Africa. Sierra Leone has no national hepatitis B strategy plan or high quality estimates of prevalence. Healthcare workers are perceived as an at-risk group for hepatitis B. We assessed the prevalence of hepatitis B among healthcare workers at two hospital sites in Freetown, Sierra Leone. METHODS: RESULTS: Overall, 447 participants were tested for hepatitis B. Most (90.6%, 405/447) participants were nurses, 72.3% (323/447) were female and 71.6% (320/447) were 30 years or older. The prevalence of chronic hepatitis B ( HBsAg positivity) was 8.7% (39 / 447, 95% CI 6.3-11.7%). There was no significant difference in prevalence by sex, age group, site of work or type of job. None of the 66.7% (26 / 39) of participants with chronic hepatitis B who attended the clinic met the 2015 WHO criteria to start treatment for hepatitis B on the basis of cirrhosis. Most participants (96.9% 432 / 446) stated that they were worried about their risk of hepatitis B at work. CONCLUSIONS:
Hepatitis B is highly prevalent among healthcare workers in Sierra Leone. It is unclear whether this reflects high community prevalence or is due to occupational risk. No participants with chronic hepatitis B needed to start treatment. In order to achieve the WHO target of elimination of viral hepatitis by 2030, introduction of birth dose vaccine for infants and catch-up vaccines for healthcare workers and healthcare students, together with a national hepatitis B screen and treat programme is advisable for Sierra Leone.
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Authors | Thomas A Massaquoi, Rachael M Burke, Guang Yang, Suliaman Lakoh, Stephen Sevalie, Bo Li, Hongjun Jia, Lei Huang, Gibrilla F Deen, Fenella Beynon, Foday Sahr |
Journal | PloS one
(PLoS One)
Vol. 13
Issue 8
Pg. e0201820
( 2018)
ISSN: 1932-6203 [Electronic] United States |
PMID | 30096162
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Antibodies, Viral
(blood)
- Cross-Sectional Studies
- Female
- Health Personnel
- Hepatitis B, Chronic
(epidemiology)
- Humans
- Male
- Prevalence
- Sierra Leone
(epidemiology)
- Urban Population
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