Abstract | PURPOSE: MATERIALS AND METHODS: In a crossover metabolic study 13 recurrent calcium phosphate stone formers without hypercalciuria were evaluated at the end of 3, 1-week study phases during which they consumed a fixed metabolic diet and received assigned study medications, including citric acid 30 mEq twice daily, potassium citrate 20 mEq twice daily or matching placebo. We collected 24-hour urine specimens to perform urine chemistry studies and calculate calcium phosphate saturation indexes. RESULTS: CONCLUSIONS:
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Authors | Steeve Doizi, John R Poindexter, Margaret S Pearle, Francisco Blanco, Orson W Moe, Khashayar Sakhaee, Naim M Maalouf |
Journal | The Journal of urology
(J Urol)
Vol. 200
Issue 6
Pg. 1278-1284
(12 2018)
ISSN: 1527-3792 [Electronic] United States |
PMID | 30036516
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2018 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Calcium Chelating Agents
- Calcium Phosphates
- Placebos
- Citric Acid
- Potassium Citrate
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Topics |
- Adult
- Calcium Chelating Agents
(administration & dosage)
- Calcium Phosphates
(urine)
- Citric Acid
(administration & dosage)
- Cross-Over Studies
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Humans
- Male
- Middle Aged
- Placebos
(administration & dosage)
- Potassium Citrate
(administration & dosage)
- Treatment Outcome
- Urinary Calculi
(chemistry, epidemiology, prevention & control, urine)
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