[Preoperative irradiation of laryngeal cancer patients under different oxygen regimens].

Abstract

Radiation therapy under the conditions of hyperbaric oxygenation (HBO) using the method of mean fractionation (3.3 Gy 3 times a week up to the summary dose of 33 Gy) was employed to overcome tumor hypoxia and to raise selectively radiosensitivity of laryngeal cancer. A randomized study of 120 patients has shown that the use of radiation therapy under HBO conditions makes it possible to reduce the frequency of radiation reactions, to increase tumor resorption and the degree of radiation damage, to reduce the frequency of postoperative purulent complications, and to prevent the occurrence of early and late recurrences and metastases.

• Authors: S L Dar'ialova, P G Bitiutskiĭ, V A Sukirko, A L Klochikhin, G A Frank
• Journal: Meditsinskaia radiologiia (Med Radiol (Mosk)) Vol. 30 Issue 9 Pg. 10-5 (Sep 1985) ISSN: 0025-8334 [Print] Russia (Federation)
• Vernacular Title: Predoperatsionnoe obluchenie bol'nykh rakom gortani pri razlichnom kislorodnom rezhime.
• PMID: 2995755 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)

Topics

• Adult
• Aged
• Carcinoma, Basal Cell (mortality, pathology, therapy)
• Carcinoma, Squamous Cell (mortality, pathology, therapy)
• Female
• Histiocytoma, Benign Fibrous (mortality, pathology, therapy)
• Humans
• Hyperbaric Oxygenation (methods)
• Laryngeal Neoplasms (mortality, pathology, therapy)
• Laryngectomy
• Male
• Middle Aged
• Neoplasm Staging
• Preoperative Care (methods)
• Radiotherapy Dosage
• Time Factors