Abstract | BACKGROUND: GOAL: The aim of this study was to determine the prevalence of patients without cirrhosis and CHB who developed HCC among a large cohort of HCC patients and to identify independent variables that are associated with no cirrhosis among patients with HCC. STUDY: From 2005 to 2015, hepatobiliary cancer patients seen in our liver cancer and liver transplant clinics were evaluated. Patients were included if above18 years old and had histologically confirmed HCC from liver biopsy, resection specimen, or explanted livers. Patients with CHB, non-HCC tumors, or missing paired tumor and nontumor liver histology were excluded. Demographic information, pertinent laboratory values, and comorbid conditions were recorded. Potential predictors were evaluated using both backward stepwise logistic regression model and classification tree model. RESULTS: CONCLUSIONS:
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Authors | Jennifer Phan, Vivian Ng, Alan Sheinbaum, Sam French, Gina Choi, Mohamed El Kabany, Francisco Durazo, Sammy Saab, Myron Tong, Ronald Busuttil, Steven-Huy Han |
Journal | Journal of clinical gastroenterology
(J Clin Gastroenterol)
Vol. 53
Issue 4
Pg. 309-313
(04 2019)
ISSN: 1539-2031 [Electronic] United States |
PMID | 29912756
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Alanine Transaminase
(blood)
- Carcinoma, Hepatocellular
(epidemiology, etiology)
- Case-Control Studies
- Cohort Studies
- Disease Progression
- Female
- Humans
- Hyperlipidemias
(complications, epidemiology)
- Liver Cirrhosis
(epidemiology)
- Liver Neoplasms
(epidemiology, etiology)
- Male
- Middle Aged
- Non-alcoholic Fatty Liver Disease
(complications, epidemiology)
- Risk Factors
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