Objective:To study the clinical effect of
mometasone furoate nasal spray combined with
montelukast in the treatment of adenoid
hypertrophy in children.Method:One hundred and thirty eight cases with adenoid
hypertrophy were randomly divided into two groups, 69 cases in each group; the control group were treated with
mometasone furoate nasal spray alone; the observation group were treated with
mometasone furoate combined with oral
montelukast. Adenoid nasopharynx ratio (A/N), and the proportion of overall recurrence
after treatment of
nasal obstruction were compared, also with
snoring,
mouth breathing rate, life quality score before and
after treatment in the two groups, and finally compared the clinical total effective ratio.Result:Compared with before treatment, A/N of two groups of patients were significantly decreased, and the observation group decreased more significantly, the difference between the two groups was significant (P< 0.05);
nasal obstruction,
snoring,
mouth breathing rate of observation group were significantly lower than the control group, and the recurrence rate also lower than the control group, the difference was statistically significant (P< 0.05). The quality of life scores,
sleep disorder scores, physical status score and daily function score in the two groups were significantly decreased
after treatment, and in observation group the three scores were decreased more significantly, the difference between the two groups was statistically significant (P< 0.05). The total efficiency of the observation group was 94.1%, which was statistically higher than the control group (79.4%, P< 0.05).Conclusion:The clinical efficacy of
mometasone furoate nasal spray combined with
montelukast in the treatment of adenoid
hypertrophy in children is significant, which can effectively reduce the adenoid nasopharynx ratio, improve the symptoms of
snoring,
mouth breathing, nasal congestion, improve the quality of life of patients, and the effective ratio was higher than single
drug treatment, which was worthy to apply on clinic.