Neurologic manifestations of Schoenlein-Henoch purpura: report of three cases and review of the literature.
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| Abstract |
Three patients developed prominent neurologic symptoms and signs associated with Schoenlein-Henoch purpura. A 7 1/2-year-old boy was seen with status epilepticus after a 2-week history of generalized headaches, irritability, and intermittent colicky abdominal pain. A left hemiparesis and a left homonymous hemianopia with a right gaze preference that were present on initial examinations gradually resolved, but a mild left arm paresis persisted. Cutaneous, renal, and joint involvement followed initial CNS manifestations. The second patient, a 7-year-old girl, had a complex partial seizure with secondary generalization and a postictal hemiparesis seven days after presentation with classic signs of Schoenlein-Henoch purpura. Behavioral changes were noted during the acute phase of the illness. The third patient, a 13-year-old boy, developed signs of a left brachial plexopathy and transient weakness of his right leg during a complicated course of Schoenlein-Henoch purpura. Review of the world literature indicates that headaches and mental status changes are the most frequent neurologic complications of Schoenlein-Henoch purpura, followed by seizures, focal neurologic deficits, mononeuropathies, and polyradiculoneuropathies. The vasculitis of Schoenlein-Henoch purpura can involve the nervous system and may add significantly to the morbidity of the illness.
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| Authors | A L Belman, C R Leicher, S L Moshé, A P Mezey |
| Journal | Pediatrics (Pediatrics) Vol. 75 Issue 4 Pg. 687-92 (Apr 1985) ISSN: 0031-4005 [Print] United States |
| PMID | 2984637 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.) |
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