| Abstract | We detected cytosol estrogen receptors in a malignant cystosarcoma phyllodes and succeeded in serial transplantations into athymic nude mice. The tumors of this transplantable strain (MC-3-JCK) have the same histologic features as the original tumors, and retain significant amounts of cytosol estrogen receptors. This strain appears to provide a useful experimental model for the study of biologic and therapeutic aspects of human cystosarcoma phyllodes of the breast. |
| Authors | Y Tokuda, M Kubota, Y Ueyama, K Maruo, J Hata, N Tamaoki, T Tajima, T Mitomi |
| Journal | Cancer
(Cancer)
Vol. 55
Issue 2
Pg. 370-4
(Jan 15 1985)
ISSN: 0008-543X UNITED STATES |
| PMID | 2981144
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
|
| Chemical References |
|
| Topics |
- Adult
- Animals
- Breast Neoplasms
(analysis, pathology)
- Cytosol
(analysis)
- Female
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Neoplasm Transplantation
- Phyllodes Tumor
(analysis, pathology)
- Receptors, Estrogen
(analysis)
- Transplantation, Heterologous
|
