Abstract | OBJECTIVE: To evaluate the relationships of depression and anxiety symptoms with cardiovascular disease (CVD) risk factors and measures of vascular health in youth. STUDY DESIGN: Participants (n = 202) were 8- to 18-year-olds from a cross-sectional study evaluating cardiovascular health across a wide range of body mass index values (normal weight to severe obesity). CVD risk measurement included blood pressure, fasting lipids, glucose, insulin, carotid artery intima-media thickness, compliance and distensibility, brachial artery flow-mediated dilation, carotid-radial artery pulse wave velocity, body fat percentage, and a metabolic syndrome cluster score. Anxiety and depression symptoms were self-reported on the Screen for Child Anxiety Related Disorders and Center for Epidemiological Studies Depression Scale for Children. Two sets of adjustment variables were used in evaluation of differences between those with and without anxiety or depression symptomatology for the CVD risk factor and vascular outcomes. The first set included adjustment for Tanner stage, sex, and race; the second was additionally adjusted for percent body fat. RESULTS: CONCLUSIONS: When accounting for body fat, we found no clear relationship of self-reported depression or anxiety symptoms with CVD risk factors or vascular health in youth.
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Authors | Amy C Gross, Alexander M Kaizer, Justin R Ryder, Claudia K Fox, Kyle D Rudser, Donald R Dengel, Aaron S Kelly |
Journal | The Journal of pediatrics
(J Pediatr)
Vol. 199
Pg. 85-91
(08 2018)
ISSN: 1097-6833 [Electronic] United States |
PMID | 29754863
(Publication Type: Journal Article, Multicenter Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2018 Elsevier Inc. All rights reserved. |
Topics |
- Adolescent
- Anxiety
(epidemiology, etiology)
- Body Weight
- Cardiovascular Diseases
(epidemiology, etiology)
- Child
- Cross-Sectional Studies
- Depression
(epidemiology, etiology)
- Female
- Humans
- Incidence
- Male
- Mental Health
- Pediatric Obesity
(complications, epidemiology, psychology)
- Prognosis
- Risk Factors
- United States
(epidemiology)
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