Primary irritant effect of 3,4,5-trichloropyridazine.

Abstract

A primary irritant dermatitis to 3,4,5-trichloropyridazine was observed on the hands of a chemist after accidental exposure. Healing was rapid in comparison to a report on 3,4,6-trichloropyridazine toxicity. Prompt treatment with a potent topical corticosteroid, wet soaks, and an oral antihistamine brought resolution within 14 days.

• Authors: T G Warshaw
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 18 Issue 5 Pg. 257-8 (May 1988) ISSN: 0105-1873 [Print] England
• PMID: 2970931 (Publication Type: Case Reports, Journal Article)

Chemical References

• Irritants
• Pyridazines
• 3,4,5-trichloropyridazine
• 3,4,6-trichloropyridazine
• Diphenhydramine
• Clobetasol

Topics

• Administration, Cutaneous
• Clobetasol (therapeutic use)
• Dermatitis, Contact (drug therapy, etiology)
• Dermatitis, Occupational (etiology)
• Diphenhydramine (therapeutic use)
• Humans
• Irritants
• Male
• Middle Aged
• Protective Clothing
• Pyridazines (adverse effects)