| Abstract | Retinoids are potent therapuetic agents that have been found to be effective in a variety of skin diseases. They are of benefit in various forms of severe psoriasis. With severe plaque psoriasis, they are used most effectively in combination with other forms of therapy, such as phototherapy. With generalized pustular psoriasis, they are effective monotherapy and are frequently helpful for the control of exfoliative psoriasis. A variety of new retinoid analogs have been studied in clinical investigations. This article discusses important aspects of the use of etretinate, isotretinoin, acitretin, and arotinoid ethyl ester in the treatment of severe forms of psoriasis. |
| Authors | N J Lowe, V Lazarus, L Matt
(Affiliation: Dermatology Program, University of California, Los Angeles School of Medicine 90024.)
|
| Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 19
Issue 1 Pt 2
Pg. 186-91
(Jul 1988)
ISSN: 0190-9622 UNITED STATES |
| PMID | 2970476
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
|
| Chemical References |
- Tretinoin
- Isotretinoin
- Etretinate
- Acitretin
|
| Topics |
- Acitretin
- Etretinate
(administration & dosage, adverse effects, therapeutic use)
- Humans
- Isomerism
- Isotretinoin
- Psoriasis
(drug therapy)
- Tretinoin
(analogs & derivatives, therapeutic use)
|
