[A Case of Sigmoid Colon Cancer with Locally Advanced Infiltration Curatively Resected after CapeOX Therapy].

Abstract

A 68-year-old man presented with malaise and abdominal swelling.Lower gastrointestinal endoscopy revealed a type 2 circumferential sigmoid colon cancer.Computed tomography suggested the cancer infiltrating bladder and abdominal wall with abscess.Because of locally advanced infiltration, the patient was treated with capecitabine plus oxaliplatin(CapeOX) plus bevacizumab therapy after loop-colostomy.After 2 courses of chemotherapy, a CT revealed tumor reduction and increased abscess, which was punctured drainage.After 4 courses of chemotherapy, a CT revealed abscess reduction, we tried to operation.Sigmoidectomy with combined resection of abdominal wall and bladder total hysterectomy and fascia lata grafting were performed.The pathological diagnosis was tub1, T4b, ly2, v2, PN0, N0, M0, Stage II, pR0, Grade I a.We reported a case of curative resection of locally advanced sigmoid colon cancer treated with combined resection of bladder and abdominal wall after CapeOX therapy.

• Authors: Yuki Suematsu, Mao Nakayama, Shunsuke Yamagishi, Hiroyuki Saito, Miyuki Takahashi, Kyohei Kanematsu, Michiko Fukabori, Kazuhiko Wakabayashi, Yutaka Itoh
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 45 Issue 3 Pg. 542-544 (Mar 2018) ISSN: 0385-0684 [Print] Japan
• PMID: 29650932 (Publication Type: Case Reports, Journal Article)

Chemical References

• Organoplatinum Compounds
• Oxaliplatin
• Capecitabine

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Capecitabine (administration & dosage)
• Humans
• Male
• Neoplasm Staging
• Organoplatinum Compounds (administration & dosage)
• Oxaliplatin
• Sigmoid Neoplasms (diagnosis, drug therapy, pathology, surgery)
• Treatment Outcome