Abstract |
57 patients with disseminated tumors of various sites received 10 daily doses of 600 mg/m2 leakadin intravenously. The immunostimulating effect was observed (OKT4/OKT8 normalization). The data on leakadin pharmacokinetics are discussed.
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Authors | A M Garin, M R Lichinitser, N V Dmitrieva, B I Rubtsov, N V Leneva |
Journal | Voprosy onkologii
(Vopr Onkol)
Vol. 34
Issue 2
Pg. 192-6
( 1988)
ISSN: 0507-3758 [Print] Russia (Federation) |
Vernacular Title | Biologicheskie éffekty leakadina. |
PMID | 2964757
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Adjuvants, Immunologic
- Antineoplastic Agents
- Aziridines
- Azirines
- Leakadine
|
Topics |
- Adjuvants, Immunologic
(pharmacokinetics, therapeutic use)
- Adult
- Animals
- Antineoplastic Agents
(pharmacokinetics, therapeutic use)
- Aziridines
(pharmacokinetics, therapeutic use)
- Azirines
(therapeutic use)
- Humans
- Killer Cells, Natural
- Leukocyte Count
- Mice
- Middle Aged
- Neoplasms
(blood, drug therapy)
- Neoplasms, Experimental
(blood, drug therapy)
- T-Lymphocytes, Regulatory
|