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[Biological effects of leakadin].

Abstract
57 patients with disseminated tumors of various sites received 10 daily doses of 600 mg/m2 leakadin intravenously. The immunostimulating effect was observed (OKT4/OKT8 normalization). The data on leakadin pharmacokinetics are discussed.
AuthorsA M Garin, M R Lichinitser, N V Dmitrieva, B I Rubtsov, N V Leneva
JournalVoprosy onkologii (Vopr Onkol) Vol. 34 Issue 2 Pg. 192-6 ( 1988) ISSN: 0507-3758 [Print] Russia (Federation)
Vernacular TitleBiologicheskie éffekty leakadina.
PMID2964757 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Adjuvants, Immunologic
  • Antineoplastic Agents
  • Aziridines
  • Azirines
  • Leakadine
Topics
  • Adjuvants, Immunologic (pharmacokinetics, therapeutic use)
  • Adult
  • Animals
  • Antineoplastic Agents (pharmacokinetics, therapeutic use)
  • Aziridines (pharmacokinetics, therapeutic use)
  • Azirines (therapeutic use)
  • Humans
  • Killer Cells, Natural
  • Leukocyte Count
  • Mice
  • Middle Aged
  • Neoplasms (blood, drug therapy)
  • Neoplasms, Experimental (blood, drug therapy)
  • T-Lymphocytes, Regulatory

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