| Abstract | 50, 100 or 150 micrograms/100 g body weight/day of very pure 3,3',5' triiodo-L-thyronine (rT3), obtained from a new synthetic method, was intraperitoneally administered in male Wistar rats for 5 weeks. Serum total thyroxine (T4), free thyroxine (FT4) and total 3,5,3' triiodo-L-thyronine (T3) concentrations were increased with all the doses of rT3. Free T3 (FT3) was also but non-significantly elevated. Different assumptions are put forward in order to explain this rT3 effect. |
| Authors | P Chomard, A Loireau, P Dumas, N Autissier
(Affiliation: Laboratoire de Chimie analytique et de Bromatologie, Faculté des Sciences Pharmaceutiques et Biologiques, Dijon.)
|
| Journal | Comptes rendus des séances de la Société de biologie et de ses filiales
(C R Seances Soc Biol Fil)
Vol. 181
Issue 4
Pg. 395-400
( 1987)
ISSN: 0037-9026 FRANCE |
| Vernacular Title | Effet de la 3,3',5' triiodo-L-thyronine (rT3) sur la concentration sérique des hormones thyroïdiennes chez le rat. |
| PMID | 2963677
(Publication Type: English Abstract, Journal Article)
|
| Chemical References |
- Thyroid Hormones
- Triiodothyronine, Reverse
- Triiodothyronine
- Thyroxine
|
| Topics |
- Animals
- Male
- Rats
- Rats, Inbred Strains
- Thyroid Hormones
(blood)
- Thyroxine
(blood)
- Time Factors
- Triiodothyronine
(blood)
- Triiodothyronine, Reverse
(administration & dosage, pharmacology)
|
