Abstract | WHAT WE ALREADY KNOW ABOUT THIS TOPIC: METHODS: Normal Sprague-Dawley rats and mice lacking guanylyl cyclase A in either endothelial cells or proximal tubular cells were challenged with lipopolysaccharide and assessed for oliguria and intratubular flow rate by intravital imaging with multiphoton microscopy. RESULTS: CONCLUSIONS:
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Authors | Hiroaki Kitamura, Daisuke Nakano, Yoshiharu Sawanobori, Takehiko Asaga, Hideki Yokoi, Motoko Yanagita, Masashi Mukoyama, Takeshi Tokudome, Kenji Kangawa, Gotaro Shirakami, Akira Nishiyama |
Journal | Anesthesiology
(Anesthesiology)
Vol. 129
Issue 2
Pg. 296-310
(08 2018)
ISSN: 1528-1175 [Electronic] United States |
PMID | 29629958
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Lipopolysaccharides
- Atrial Natriuretic Factor
- Receptors, Atrial Natriuretic Factor
- atrial natriuretic factor receptor A
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Topics |
- Acute Kidney Injury
(drug therapy, enzymology, prevention & control)
- Animals
- Atrial Natriuretic Factor
(administration & dosage)
- Disease Models, Animal
- Endothelial Cells
(drug effects, enzymology)
- Endotoxemia
(chemically induced, enzymology, prevention & control)
- Enzyme Activation
(drug effects, physiology)
- Humans
- Infusions, Intravenous
- Kidney Tubules, Proximal
(drug effects, enzymology)
- Lipopolysaccharides
(toxicity)
- Mice
- Mice, Knockout
- Rats
- Rats, Sprague-Dawley
- Receptors, Atrial Natriuretic Factor
(metabolism)
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