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Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol.

Abstract
A shipwright developed a delayed bullous irritant dermatitis from contact with a bis-tri-butyl tin oxide (TBTO) containing antifouling paint. He subsequently developed sensitization to 4-chloro-m-cresol, a constituent of a steroid cream. No cross sensitivity to 4-chloro-3,5 xylenol was seen. Low concentrations of 4-chloro-m-cresol in pet. may elicit a true positive reaction. TBTO is a strong irritant which will produce delayed bullous reactions in industrial use and on patch testing at 0.1% aqueous.
AuthorsP G Lewis, E A Emmett
JournalContact dermatitis (Contact Dermatitis) Vol. 17 Issue 3 Pg. 129-32 (Sep 1987) ISSN: 0105-1873 [Print] England
PMID2960483 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cresols
  • Trialkyltin Compounds
  • bis(tri-n-butyltin)oxide
  • chlorocresol
Topics
  • Adult
  • Cresols (adverse effects, therapeutic use)
  • Dermatitis, Contact (drug therapy, etiology)
  • Dermatitis, Occupational (chemically induced, drug therapy)
  • Drug Eruptions (diagnosis, etiology)
  • Humans
  • Male
  • Patch Tests
  • Trialkyltin Compounds (adverse effects)

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