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Protective effects of selective inhibitor of thromboxane synthetase (OKY-046) and thromboxane antagonist (ONO-3708) on ischemia-induced mitochondrial dysfunction in canine heart.

AuthorsT Ito, Y Ito, T Torii, N Hieda, Y Toki, Y Miyazaki, H Hashimoto, K Ogawa, T Satake
JournalAdvances in prostaglandin, thromboxane, and leukotriene research (Adv Prostaglandin Thromboxane Leukot Res) Vol. 17A Pg. 392-6 ( 1987) ISSN: 0732-8141 [Print] United States
PMID2959085 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Acrylates
  • Methacrylates
  • Thromboxane A2
  • ONO 3708
  • Thromboxane-A Synthase
  • ozagrel
Topics
  • Acrylates (pharmacology)
  • Animals
  • Coronary Disease (metabolism, prevention & control)
  • Dogs
  • In Vitro Techniques
  • Methacrylates (pharmacology)
  • Mitochondria, Heart (drug effects, metabolism)
  • Oxygen Consumption (drug effects)
  • Thromboxane A2 (analogs & derivatives, antagonists & inhibitors, pharmacology)
  • Thromboxane-A Synthase (antagonists & inhibitors)

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