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Abolition of Holter monitor-detected silent myocardial ischemia after percutaneous transluminal coronary angioplasty.

Abstract
Twenty-four hour Holter ambulatory electrocardiographic recordings were obtained before and after successful coronary angioplasty in 36 patients. Twenty-five patients had one vessel, 10 had two vessel and 1 had three vessel coronary artery disease. Holter monitor-detected myocardial ischemia, defined as ST segment depression or elevation greater than or equal to 1 mm, was present in 10 patients (28%). These 10 patients had a total of 39 ischemic episodes of 3 to 144 minutes' duration, with a total cumulative duration of 398 minutes. None of the 10 had Holter monitor-detected ischemia after successful angioplasty (p less than 0.01). Treadmill exercise duration increased by 29% after coronary angioplasty (p less than 0.01), and peak exercise heart rate-systolic blood pressure product increased by 27% (p less than 0.01). Thus, Holter monitor-detected myocardial ischemia is a relatively uncommon finding in patients with predominant single vessel coronary artery disease undergoing coronary angioplasty. When such ischemia is present, it is eliminated by successful coronary angioplasty.
AuthorsM A Josephson, K Nademanee, V Intarachot, H Lewis, B N Singh
JournalJournal of the American College of Cardiology (J Am Coll Cardiol) Vol. 10 Issue 3 Pg. 499-503 (Sep 1987) ISSN: 0735-1097 [Print] United States
PMID2957411 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
Topics
  • Adult
  • Aged
  • Angiography
  • Angioplasty, Balloon
  • Constriction, Pathologic
  • Coronary Disease (diagnostic imaging, physiopathology, therapy)
  • Electrocardiography
  • Heart (physiopathology)
  • Hemodynamics
  • Humans
  • Middle Aged
  • Monitoring, Physiologic
  • Physical Exertion

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