Abstract |
Seven patients, mean age 8 +/- 3.6 years, with clinical and hemodynamic diagnoses of discrete subaortic stenosis were treated by percutaneous transluminal balloon dilatation ( PTBD) of the membrane during cardiac catheterization. One patient had an associated aortic coarctation that was first dilated. After PTBD left ventricular (LV) systolic pressure decreased significantly, from 181 +/- 25 to 139 +/- 11 mm Hg (p less than 0.005); peak gradient diminished from 65 +/- 18 to 12 +/- 9 mm Hg (p less than 0.001). Mild aortic regurgitation was present in 6 patients during basal conditions. After PTBD, the same degree of regurgitation was observed in all but 1 patient, in whom it disappeared. There were no major complications. Clinical observations after PTBD were consistent with hemodynamic findings. Precordial thrill always disappeared and the peak murmur became earlier in systole. In 2 patients the discrete subaortic stenosis was clearly visualized at 2-dimensional echocardiography as a fixed subvalvular structure throughout the cardiac cycle. After dilatation this was only identifiable at its implantation base; during contraction there was no fixed structure at the LV outflow tract. Four patients were hemodynamically reevaluated 6.7 +/- 1.7 months later and were found to have LV pressure relief and a degree of aortic regurgitation similar to those observed immediately after PTBD.
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Authors | J Suárez de Lezo, M Pan, M Sancho, N Herrera, J Arizon, M Franco, M Concha, F Valles, A Romanos |
Journal | The American journal of cardiology
(Am J Cardiol)
Vol. 58
Issue 7
Pg. 619-21
(Sep 15 1986)
ISSN: 0002-9149 [Print] United States |
PMID | 2944370
(Publication Type: Journal Article)
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Topics |
- Angioplasty, Balloon
- Aortic Stenosis, Subvalvular
(physiopathology, therapy)
- Cardiomyopathy, Hypertrophic
(therapy)
- Child
- Child, Preschool
- Echocardiography
- Hemodynamics
- Humans
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