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Unprecedented response to combination BRAF and MEK inhibitors in adult anaplastic ganglioglioma.

AuthorsBenjamin Beland, Roger Y Tsang, Garnette Sutherland
JournalJournal of neuro-oncology (J Neurooncol) Vol. 137 Issue 3 Pg. 667-669 (May 2018) ISSN: 1573-7373 [Electronic] United States
PMID29335912 (Publication Type: Case Reports, Letter)
Chemical References
  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf
  • MAP Kinase Kinase Kinases
Topics
  • Antineoplastic Agents (therapeutic use)
  • Brain Neoplasms (diagnostic imaging, enzymology, genetics, therapy)
  • Combined Modality Therapy
  • Female
  • Ganglioglioma (diagnostic imaging, enzymology, genetics, therapy)
  • Humans
  • MAP Kinase Kinase Kinases (antagonists & inhibitors, metabolism)
  • Middle Aged
  • Neoplasm Metastasis
  • Protein Kinase Inhibitors (adverse effects, therapeutic use)
  • Proto-Oncogene Proteins B-raf (antagonists & inhibitors, genetics, metabolism)

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