Nanoliposomes as the adjuvant delivery systems in cancer immunotherapy.

Abstract

Cancer immunotherapy is one of the commonly used methods in the treatment of cancer. The aim of this approach is to strengthen or restore immune function for effective diagnosis of aberrant cells antigens. For this reason, cancer specific peptides or proteins are used as antigens to induce an immune response capable of removing cancer cells. Liposomal formulations are an important carrier system frequently used for delivery of antigen because the specific properties of this component such as lipid composition, charge, size, encapsulation of antigens, or adjuvants can be changed. Among different types of liposomal formulations, the use of cationic and pH-sensitive nanoliposomes has been markedly increased for liposome-based vaccines. In this review, we describe the properties of nanoliposomes as delivery systems for cancer immunotherapy.

• Authors: Parvin Zamani, Amir Abbas Momtazi-Borojeni, Maryam Ebrahimi Nik, Reza Kazemi Oskuee, Amirhossein Sahebkar
• Journal: Journal of cellular physiology (J Cell Physiol) Vol. 233 Issue 7 Pg. 5189-5199 (07 2018) ISSN: 1097-4652 [Electronic] United States
• PMID: 29215747 (Publication Type: Journal Article, Review)
• Copyright: © 2017 Wiley Periodicals, Inc.

Chemical References

• Adjuvants, Immunologic
• Liposomes

Topics

• Adjuvants, Immunologic (chemistry, therapeutic use)
• Drug Delivery Systems
• Humans
• Immunotherapy
• Liposomes (chemistry, therapeutic use)
• Nanoparticles (chemistry, therapeutic use)
• Neoplasms (drug therapy, immunology)