Abstract | INTRODUCTION: METHODS AND ANALYSIS: A systematic literature search will be performed using the EMBASE, MEDLINE, and Cochrane databases to identify relevant articles published in any language. Randomized clinical trials, case series, and case reports of PD-1 and PD-L1 inhibitors in the treatment of nonsmall cell lung cancer will be included. All meta-analyses will be performed using RevMan software. The quality of the studies will be evaluated using the guidelines listed in the Cochrane Handbook. If the necessary data are available, then subgroup analyses will be performed for high-, median-, and low-dose cohorts. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statements will be followed until the findings of the systematic review and meta-analysis are reported. CONCLUSIONS:
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Authors | Xiaoying Sun, Raheleh Roudi, Shangya Chen, Bin Fan, Hong Jin Li, Min Zhou, Xin Li, Bin Li |
Journal | Medicine
(Medicine (Baltimore))
Vol. 96
Issue 44
Pg. e8407
(Nov 2017)
ISSN: 1536-5964 [Electronic] United States |
PMID | 29095271
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
- Antibodies, Monoclonal
- B7-H1 Antigen
- CD274 protein, human
- Immunologic Factors
- PDCD1 protein, human
- Programmed Cell Death 1 Receptor
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Topics |
- Antibodies, Monoclonal
(adverse effects)
- B7-H1 Antigen
(antagonists & inhibitors)
- Carcinoma, Non-Small-Cell Lung
(drug therapy)
- Clinical Protocols
- Humans
- Immunologic Factors
(adverse effects)
- Programmed Cell Death 1 Receptor
(antagonists & inhibitors)
- Systematic Reviews as Topic
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