HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Psychotic patients who become worse on neuroleptics.

Abstract
We describe a group of psychotic patients who became worse early in the course of neuroleptic treatment. Characteristics of this group were: predominantly female sex, relatively brief onset, family history of affective disorder, hypomotoric presentation, and severe neuroleptic side effects. We propose that some patients with affective psychoses are uniquely susceptible to profound blockade of the nigrostriatal dopaminergic system by neuroleptics.
AuthorsM B Bowers Jr, M E Swigar
JournalJournal of clinical psychopharmacology (J Clin Psychopharmacol) Vol. 8 Issue 6 Pg. 417-21 (Dec 1988) ISSN: 0271-0749 [Print] United States
PMID2906948 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antipsychotic Agents
  • Benztropine
  • Thiothixene
  • Haloperidol
  • Chlorpromazine
Topics
  • Adolescent
  • Adult
  • Antipsychotic Agents (adverse effects, therapeutic use)
  • Benztropine (therapeutic use)
  • Chlorpromazine (adverse effects)
  • Dyskinesia, Drug-Induced (etiology)
  • Female
  • Haloperidol (adverse effects)
  • Humans
  • Male
  • Psychoses, Substance-Induced (etiology)
  • Psychotic Disorders (drug therapy)
  • Thiothixene (adverse effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: