Urinary estrone glucuronide, pregnanediol glucuronide and human chorionic gonadotrophin in threatened abortion.

Estimations of urinary estrone glucuronide, pregnanediol glucuronide and human chorionic gonadotrophin were carried out by ELISA to see their potential in predicting an abnormal outcome in cases with vaginal bleeding in early pregnancy. Reference values were set up with samples from women without bleeding in present or past pregnancies and with normal ultrasonic findings. None of the parameters were found to be sensitive enough to predict an abnormal outcome. However, predictability of an abnormal value was found to be 95% for estrone-3-glucuronide (E1G), 93% for pregnanediol glucuronide (PdG) and 87% for human chorionic gonadotrophin (hCG).
AuthorsP C Ishwad, S M Chitlange, U M Joshi, V Chowdhury, A C Mehta
JournalInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (Int J Gynaecol Obstet) Vol. 27 Issue 1 Pg. 107-11 (Aug 1988) ISSN: 0020-7292 [Print] IRELAND
PMID2905284 (Publication Type: Journal Article)
Chemical References
  • Chorionic Gonadotropin
  • pregnanediol-3 alpha-glucuronide
  • estrone-3-glucuronide
  • Estrone
  • Pregnanediol
  • Abortion, Missed (urine)
  • Abortion, Threatened (urine)
  • Chorionic Gonadotropin (urine)
  • Enzyme-Linked Immunosorbent Assay
  • Estrone (analogs & derivatives, urine)
  • Female
  • Humans
  • Pregnancy
  • Pregnanediol (analogs & derivatives, urine)

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