New directions and dimensions in the treatment of allergic rhinitis.

Abstract

Physicians who treat patients with allergic rhinitis have a number of therapeutic options, including antihistamines, decongestants, cromolyn, anticholinergics, corticosteroids, and immunotherapy. Antihistamines are widely used for the treatment of mild allergic rhinitis and are often effective, although more severe cases will require other medications. The newer antihistamines may induce less drowsiness, which is the most prominent side effect of the older antihistamines. Topical nasal decongestants give fast relief from nasal congestion, but their overuse may result in rebound congestion. Because their efficacy in allergic rhinitis is variable, oral decongestants are usually used in combination with antihistamines. Nasal cromolyn is effective for many patients with allergic rhinitis, but its effect is variable and it is useful in severe allergic rhinitis.

• Authors: W Busse
• Journal: The Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 82 Issue 5 Pt 2 Pg. 890-900 (Nov 1988) ISSN: 0091-6749 [Print] United States
• PMID: 2903877 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Inflammatory Agents
• Glucocorticoids
• Histamine H1 Antagonists

Topics

• Administration, Topical
• Anti-Inflammatory Agents (therapeutic use)
• Glucocorticoids
• Histamine H1 Antagonists (therapeutic use)
• Humans
• Rhinitis, Allergic, Perennial (drug therapy)