Diagnostic significance of octadeca-9,11-dienoic acid in cervical neoplasia.

Abstract

The percentage molar ratio (%MR) of the 9,11 and 9,12 isomers of octadecadienoic acid was determined in cervical exfoliated cells from 148 subjects, of whom 27 had cytologically proven intraepithelial neoplasia and in cervical biopsy specimens from 43 subjects, of whom 24 had histologically diagnosed cervical intraepithelial neoplasia. The %MR in both cervical biopsy specimens and exfoliated cells did not significantly differ in subjects with or without cervical intraepithelial neoplasia. The measurement of the %MR of 9,11:9,12 octadecadienoic acid has no role in the detection of cervical intraepithelial neoplasia.

• Authors: A J Green, B J Starkey, S P Halloran, G McKee, C J Sutton, B T Manners, A W Walker
• Journal: Lancet (London, England) (Lancet) Vol. 2 Issue 8606 Pg. 309-11 (Aug 06 1988) ISSN: 0140-6736 [Print] England
• PMID: 2899722 (Publication Type: Journal Article)

Chemical References

• Linoleic Acids
• Linoleic Acids, Conjugated
• 9,11-linoleic acid

Topics

• Female
• Humans
• Linoleic Acids (analysis)
• Linoleic Acids, Conjugated
• Uterine Cervical Neoplasms (analysis)