Actions of deltamethrin and tralomethrin on cholinergic synaptic transmission in the central nervous system of the cockroach (Periplaneta americana).

Abstract	Deltamethrin (RU 22974) and tralomethrin isomers (RU 24784 and RU 24785) block transmission at the cercal-afferent giant-interneuron synapses of the cockroach, when bath-applied to the desheathed ganglion at micromolar concentrations. The time-course of the events leading to the blockage suggests two possible target sites: one located presynaptically and the other situated on postsynaptic membranes.
Authors	B Hue, L Mony
Journal	Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology (Comp Biochem Physiol C Comp Pharmacol Toxicol) Vol. 86 Issue 2 Pg. 349-52 ( 1987) ISSN: 0742-8413 [Print] England
PMID	2882930 (Publication Type: Journal Article)
Chemical References	Nitriles Pyrethrins decamethrin Acetylcholine tralomethrin
Topics	Acetylcholine (pharmacology) Animals Cholinergic Fibers (drug effects) Cockroaches (physiology) In Vitro Techniques Nitriles Periplaneta (physiology) Pyrethrins (pharmacology) Synaptic Membranes (drug effects) Synaptic Transmission (drug effects) Time Factors

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