Abstract |
Deltamethrin (RU 22974) and tralomethrin isomers (RU 24784 and RU 24785) block transmission at the cercal-afferent giant-interneuron synapses of the cockroach, when bath-applied to the desheathed ganglion at micromolar concentrations. The time-course of the events leading to the blockage suggests two possible target sites: one located presynaptically and the other situated on postsynaptic membranes.
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Authors | B Hue, L Mony |
Journal | Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
(Comp Biochem Physiol C Comp Pharmacol Toxicol)
Vol. 86
Issue 2
Pg. 349-52
( 1987)
ISSN: 0742-8413 [Print] England |
PMID | 2882930
(Publication Type: Journal Article)
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Chemical References |
- Nitriles
- Pyrethrins
- decamethrin
- Acetylcholine
- tralomethrin
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Topics |
- Acetylcholine
(pharmacology)
- Animals
- Cholinergic Fibers
(drug effects)
- Cockroaches
(physiology)
- In Vitro Techniques
- Nitriles
- Periplaneta
(physiology)
- Pyrethrins
(pharmacology)
- Synaptic Membranes
(drug effects)
- Synaptic Transmission
(drug effects)
- Time Factors
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