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[Treatment of urticaria with the new H1 antihistaminic astemizole--with special reference to the time of onset of effect and maximum effect].

Abstract
20 patients, 12 suffering from chronic urticaria, 2 from acute urticaria, 1 from pressure urticaria, 2 from cold urticaria and 3 from urticaria factitia were treated in an open pilot study with the new H1-antihistamine Astemizole. The dosage was in all cases 1 X 10 mg per day. The onset of action as well as the efficacy maximum were registered. Astemizole proved in this study to be a very effective antihistamine being able to achieve good results even in hard to cure cases like cold urticaria. On the 1. day 35% of the patients had noticed an onset of action. 75% of the patients had an onset of action within the first 2 days. The efficacy maximum was achieved within the first 2 days in 60% of the patients.
AuthorsK Kurz
JournalZeitschrift fur Hautkrankheiten (Z Hautkr) Vol. 61 Issue 22 Pg. 1646-53 (Nov 15 1986) ISSN: 0301-0481 [Print] Germany
Vernacular TitleUrtikaria-Behandlung mit dem neuen H1-Antihistaminikum Astemizol--Besondere Berücksichtigung des zeitlichen Verlaufes von Wirkungseintritt und Wirkungsmaximum.
PMID2880431 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Benzimidazoles
  • Histamine H1 Antagonists
  • Astemizole
Topics
  • Adolescent
  • Adult
  • Angioedema (drug therapy)
  • Astemizole
  • Benzimidazoles (therapeutic use)
  • Female
  • Histamine H1 Antagonists (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Time Factors
  • Urticaria (drug therapy)

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