Abstract |
20 patients, 12 suffering from chronic urticaria, 2 from acute urticaria, 1 from pressure urticaria, 2 from cold urticaria and 3 from urticaria factitia were treated in an open pilot study with the new H1-antihistamine Astemizole. The dosage was in all cases 1 X 10 mg per day. The onset of action as well as the efficacy maximum were registered. Astemizole proved in this study to be a very effective antihistamine being able to achieve good results even in hard to cure cases like cold urticaria. On the 1. day 35% of the patients had noticed an onset of action. 75% of the patients had an onset of action within the first 2 days. The efficacy maximum was achieved within the first 2 days in 60% of the patients.
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Authors | K Kurz |
Journal | Zeitschrift fur Hautkrankheiten
(Z Hautkr)
Vol. 61
Issue 22
Pg. 1646-53
(Nov 15 1986)
ISSN: 0301-0481 [Print] Germany |
Vernacular Title | Urtikaria-Behandlung mit dem neuen H1-Antihistaminikum Astemizol--Besondere Berücksichtigung des zeitlichen Verlaufes von Wirkungseintritt und Wirkungsmaximum. |
PMID | 2880431
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Benzimidazoles
- Histamine H1 Antagonists
- Astemizole
|
Topics |
- Adolescent
- Adult
- Angioedema
(drug therapy)
- Astemizole
- Benzimidazoles
(therapeutic use)
- Female
- Histamine H1 Antagonists
(therapeutic use)
- Humans
- Male
- Middle Aged
- Time Factors
- Urticaria
(drug therapy)
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